Guitarist and trumpeter try to play together in a room filled with helium?

Mar 2020
Roma, Italy
No , they wouldn't choke .... just quietly die

Choking is ..."( a person or animal) having severe difficulty in breathing because of a constricted or obstructed throat or a lack of air. ..."

Breathing air(gas) or helium with no oxygen is a very smooth and pain free way to commit suicide , you would notice nothing , the brain would just stop functioning from lack of oxygen , just the same effect as CO poisoning ... dying in a small sealed small room, by using up all the oxygen in the air would be very stressful , the build up of CO2 alerts the body to breath more quickly and panic.
Thank you. I often see people use Helium to change their voices